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Article

Potential genetic markers for nonsyndromic oral clefts in the Brazilian population: A systematic review and meta-analysis.

Birth defects research - 1 Jun 2018

Assis Machado Renato, de Toledo Isabela Porto, Martelli-Júnior Hercilio, Reis Silvia Regina, Neves Silva Guerra Eliete, Coletta Ricardo D

Abstract excerpt

BACKGROUND: Although various genes and genomic regions were described as of susceptibility for nonsyndromic oral clefts (NOC), recent reports have demonstrated significant interethnic variations in the genetic predisposition, a situation that affects the Brazilian population, one of the most admixed populations in the world. Therefore, the purpose of this review was to describe the available information on...

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Bone Morphogenetic Protein 4
Brazil
Cleft Lip
Cleft Palate
Inheritance Patterns

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interferon Regulatory Factors

Methylenetetrahydrofolate Reductase (NADPH2)

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Identifiers

PMID: 29446255
DOI: 10.1002/bdr2.1208

Genes

BMP4
MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Potential genetic markers for nonsyndromic oral clefts in the Brazilian population: A systematic review and meta-analysis.PMID 29446255Read ↗

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IRF6 is a risk factor for nonsyndromic cleft lip in the Brazilian population.Semantic proximity Read ↗

Analysis of susceptibility polymorphisms for nonsyndromic cleft lip with or without cleft palate in the Brazilian population.Semantic proximity Read ↗

Ethnic Differences in the Brazilian Population Influence the Impact of BMP4 Genetic Variants on Susceptibility of Nonsyndromic Orofacial Clefts.Semantic proximity Read ↗

Evaluation of genome-wide association signals for nonsyndromic cleft lip with or without cleft palate in a multiethnic Brazilian population.Semantic proximity Read ↗

Machine learning in prediction of genetic risk of nonsyndromic oral clefts in the Brazilian population.Semantic proximity Read ↗

Polymorphisms at regions 1p22.1 (rs560426) and 8q24 (rs1530300) are risk markers for nonsyndromic cleft lip and/or palate in the Brazilian population.Semantic proximity Read ↗

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Association between the IRF6 rs2235371 polymorphism and the risk of nonsyndromic cleft lip with or without cleft palate in Chinese Han populations: A meta-analysis.Semantic proximity Read ↗

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