Association between a single-nucleotide polymorphism in the GREM1 gene and non-syndromic orofacial cleft in the Chinese population.

doi:10.1111/jop.12662

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Article

Association between a single-nucleotide polymorphism in the GREM1 gene and non-syndromic orofacial cleft in the Chinese population.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Feb 2018

Wang Xiaotong, Song Hongquan, Jiao Xiaohui, Hao Yanru, Zhang Wei, Gao Yuwei, Li Yong, Mi Na, Yan Jiaqun

Abstract excerpt

BACKGROUND: Non-syndromic orofacial cleft (NSOC) is a common craniofacial deformity among newborns. The GREM1 gene is correlated with orofacial development. The aim of our study was to investigate the association between a single-nucleotide polymorphism in the GREM1 gene and this malformation in the Chinese population. METHODS: The SNaPshot mini-sequencing technique was used to genotype the locus rs1258763 of the...

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PMID: 29149498
DOI: 10.1111/jop.12662

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GREM1
CPO

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