Article
Association of MTHFR 1298A > C Polymorphism with Susceptibility to Non-Syndromic Cleft Lip with or without Palate: A Case-Control Study and Meta-Analysis.
Fetal and pediatric pathology - 1 Feb 2021
Niktabar Seyed Mohammadreza, Aarafi Hossein, Dastgheib Seyed Alireza, Noorishadkam Mahmood, Mirjalili Seyed Reza, Lookzadeh Mohamad Hosein, Akbarian-Bafghi Mohammad Javad, Morovati-Sharifabad Majid, Neamatzadeh Hossein
Abstract excerpt
BACKGROUND: Several studies have evaluated association of the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene 1298A > C polymorphism with non-syndromic cleft lip with or without palate (NSCL ± P) susceptibility, however the results are inconsistent. MATERIALS AND METHODS: To address this issue, we performed a case-control study to evaluate the association of MTHFR 1298A > C polymorphism with NSCL ± P risk,...
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