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Article

Association of Fetal MTHFR 677C > T Polymorphism with Non-Syndromic Cleft Lip with or without Palate Risk: A Systematic Review and Meta-Analysis.

Fetal and pediatric pathology - 1 Aug 2021

Amooee Abdolhamid, Dastgheib Seyed Alireza, Niktabar Seyed Mohammadreza, Noorishadkam Mahmood, Lookzadeh Mohamad Hosein, Mirjalili Seyed Reza, Heiranizadeh Naeimeh, Neamatzadeh Hossein

Abstract excerpt

BACKGROUND: This study was conducted to estimate the precise association of fetal MTHFR 677 C > T polymorphism with risk of nonsyndromic cleft lip with or without cleft palate (NSCL ± P) using a large-scale meta-analysis. Methods: A comprehensive literature search was performed using studies published on PubMed, Science Direct, Scopus and CNKI databases up to November 1, 2019. Results: A total of 38 studies with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31880477
DOI: 10.1080/15513815.2019.1707918

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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