Article
Refining diffuse large B-cell lymphoma subgroups using integrated analysis of molecular profiles.
EBioMedicine - 1 Oct 2019
Dubois Sydney, Tesson Bruno, Mareschal Sylvain, Viailly Pierre-Julien, Bohers Elodie, Ruminy Philippe, Etancelin Pascaline, Peyrouze Pauline, Copie-Bergman Christiane, Fabiani Bettina, Petrella Tony, Jais Jean-Philippe, Haioun Corinne, Salles Gilles, Molina Thierry Jo, Leroy Karen, Tilly Hervé, Jardin Fabrice
Abstract excerpt
BACKGROUND: Gene expression profiling (GEP), next-generation sequencing (NGS) and copy number variation (CNV) analysis have led to an increasingly detailed characterization of the genomic profiles of DLBCL. The aim of this study was to perform a fully integrated analysis of mutational, genomic, and expression profiles to refine DLBCL subtypes. A comparison of our model with two recently published integrative...
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