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Article

LymphGen-Sig: Integrating genetic and transcriptional states to predict therapeutic response in DLBCL

2026-03-02

Abstract excerpt

<h4>Purpose: </h4> Genetic classification may advance precision medicine in diffuse large B-cell lymphoma (DLBCL), but existing tools like LymphGen (LG) are limited by complexity, incomplete classification, and do not incorporate non-genetic features that impact disease biology and therapeutic outcomes. To address these limitations, we developed LymphGen-sig (LGsig), a gene expression-based platform that classifie...

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Literature Corpus work
fd514d7c-58b0-56cc-9214-487a4146a400
DOI
10.64898/2026.02.20.26346725
Open publication

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LymphGen-Sig: Integrating genetic and transcriptional states to predict therapeutic response in DLBCLDOI 10.64898/2026.02.20.26346725
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