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Article

High-risk subgroup and associated genes identified by next generation sequencing in diffuse large B cell lymphoma.

BMC cancer - 23 Mar 2026

Jang Ho Cheol, Song Ga-Young, Kang Sae-Ryung, Han Seung Jung, Kim Mihee, Ahn Seo-Yeon, Jung Sung-Hoon, Ahn Jae-Sook, Lee Je-Jung, Kim Hyeoung-Joon, Yang Deok-Hwan

Abstract excerpt

PURPOSE: Diffuse large B cell lymphoma (DLBCL) displays genetic and clinical heterogeneity that limits the predictive value of cell-of-origin and LymphGen. We evaluated whether diagnostic targeted next generation sequencing (NGS) could predict outcomes and delineate high-risk subsets in routine practice. EXPERIMENTAL DESIGN: We retrospectively analyzed tumors from 106 patients. Variants with allele...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41872789
DOI: 10.1186/s12885-026-15868-9
PMCID: PMC13137617

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