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Article

A refined cell-of-origin classifier with targeted NGS and artificial intelligence shows robust predictive value in DLBCL

28 Jul 2020

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous entity of B-cell lymphoma. Cell-of-origin (COO) classification of DLBCL is required in routine practice by the World Health Organization classification for biological and therapeutic insights. Genetic subtypes uncovered recently are based on distinct genetic alterations in DLBCL, which are different from the COO subtypes defined by gene expression...

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PMID: 32722783
DOI: 10.1182/bloodadvances.2020001949

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