Article
Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma.
Scientific reports - 21 Jan 2021
Pedrosa Lucía, Fernández-Miranda Ismael, Pérez-Callejo David, Quero Cristina, Rodríguez Marta, Martín-Acosta Paloma, Gómez Sagrario, González-Rincón Julia, Santos Adrián, Tarin Carlos, García Juan F, García-Arroyo Francisco R, Rueda Antonio, Camacho Francisca I, García-Cosío Mónica, Heredero Ana, Llanos Marta, Mollejo Manuela, Piris-Villaespesa Miguel, Gómez-Codina José, Yanguas-Casás Natalia, Sánchez Antonio, Piris Miguel A, Provencio Mariano, Sánchez-Beato Margarita
Abstract excerpt
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease whose prognosis is associated with clinical features, cell-of-origin and genetic aberrations. Recent integrative, multi-omic analyses had led to identifying overlapping genetic DLBCL subtypes. We used targeted massive sequencing to analyze 84 diagnostic samples from a multicenter cohort of patients with DLBCL treated with rituximab-containing...
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