Article
Analysis of tumour ecological balance reveals resource-dependent adaptive strategies of ovarian cancer.
EBioMedicine - 1 Oct 2019
Nawaz Sidra, Trahearn Nicholas A, Heindl Andreas, Banerjee Susana, Maley Carlo C, Sottoriva Andrea, Yuan Yinyin
Abstract excerpt
BACKGROUND: Despite treatment advances, there remains a significant risk of recurrence in ovarian cancer, at which stage it is usually incurable. Consequently, there is a clear need for improved patient stratification. However, at present clinical prognosticators remain largely unchanged due to the lack of reproducible methods to identify high-risk patients. METHODS: In high-grade serous ovarian cancer patients...
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