Article

The spatial structure of the tumor immune microenvironment can explain and predict patient response in high-grade serous carcinoma

2024-01-29

Abstract excerpt

Despite ovarian cancer being the deadliest gynecological malignancy, there has been little change to therapeutic options and mortality rates over the last three decades. Recent studies indicate that the composition of the tumor immune microenvironment (TIME) influences patient outcomes but are limited by a lack of spatial understanding. We performed multiplexed ion beam imaging (MIBI) on 83 human high-grade serous...

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Literature Corpus work: 32f00829-ee44-50e3-b905-73312c1d463e
DOI: 10.1101/2024.01.26.577350

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