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Article

Revisiting ovarian cancer microenvironment: a friend or a foe?

19 Sept 2017

Abstract excerpt

Development of ovarian cancer involves the co-evolution of neoplastic cells together with the adjacent microenvironment. Steps of malignant progression including primary tumor outgrowth, therapeutic resistance, and distant metastasis are not determined solely by genetic alterations in ovarian cancer cells, but considerably shaped by the fitness advantage conferred by benign components in the ovarian stroma. As...

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PMID: 28929459
DOI: 10.1007/s13238-017-0466-7

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