Article
Correlation between female sex, IL28B genotype, and the clinical severity of bronchiolitis in pediatric patients.
Pediatric research - 1 Mar 2020
Astudillo Patricio, Angulo Jenniffer, Pino Karla, de Carvalho Joseane Biso, de Morais Guilherme Loss, Perez Sebastián, de Vasconcelos Ana Tereza Ribeiro, Ferrés Marcela, López-Lastra Marcelo
Abstract excerpt
BACKGROUND: Single-nucleotide polymorphisms (SNPs) that impact on the differential expression of interleukin 28B (IL28B) are implicated in the progression of viral-induced diseases. In this prospective longitudinal cohort study, we evaluated the association between IL28B SNPs rs12979860 and rs8099917 and the clinical outcome of bronchiolitis in pediatric patients. METHODS: A total of 682 infants suffering from...
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