Article
IL-18R1 and IL-18RAP SNPs may be associated with bronchopulmonary dysplasia in African-American infants.
Pediatric research - 1 Jan 2012
Floros Joanna, Londono Douglas, Gordon Derek, Silveyra Patricia, Diangelo Susan L, Viscardi Rose M, Worthen George S, Shenberger Jeffrey, Wang Guirong, Lin Zhenwu, Thomas Neal J
Abstract excerpt
INTRODUCTION: The genetic contribution to the development of bronchopulmonary dysplasia (BPD) in prematurely born infants is substantial, but information related to the specific genes involved is lacking. RESULTS: Genotype analysis revealed, after multiple comparisons correction, two significant single-nucleotide polymorphism (SNPs), rs3771150 (IL-18RAP) and rs3771171 (IL-18R1), in African Americans (AAs) with...
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