Article
Association between single nucleotide polymorphisms in TLR4, TLR2, TLR9, VDR, NOS2 and CCL5 genes with acute viral bronchiolitis.
Gene - 1 Mar 2018
Alvarez Alfonso Eduardo, Marson Fernando Augusto Lima, Bertuzzo Carmen Sílvia, Bastos Juliana Cristina Santiago, Baracat Emilio Carlos Elias, Brandão Marcelo Barciela, Tresoldi Antônia Teresinha, das Neves Romaneli Mariana Tresoldi, Almeida Celize Cruz Bresciani, de Oliveira Therezinha, Schlodtmann Patricia Godano, Corrêa Ester, de Miranda Maria Luisa Ferreira, Dos Reis Marcelo Conrado, De Pieri José Vicente, Arns Clarice Weis, Ribeiro José Dirceu
Abstract excerpt
BACKGROUND: Acute viral bronchiolitis is the leading cause of hospitalization among infants during the first year of life. Most infants hospitalized for bronchiolitis do not present risk factors and are otherwise healthy. Our objective was to determine the genetic features associated with the risk and a severe course of bronchiolitis. METHODS: We prospectively evaluated 181 infants with severe bronchiolitis...
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