Article
IL-8/IL-17 gene variations and the susceptibility to severe viral bronchiolitis.
Epidemiology and infection - 1 Mar 2017
Pinto L A, DE Azeredo Leitão L A, Mocellin M, Acosta P, Caballero M T, Libster R, Vargas J E, Polack F, Comaru T, Stein R T, DE Souza A P
Abstract excerpt
Clinical manifestations of acute bronchiolitis (AB) vary from minimal disease to severe respiratory failure. The response to respiratory viral infections is possibly influenced by genetic polymorphisms linked to the regulation of the inflammatory response. In the present study, we investigated whether interleukin-8 (IL-8) and interleukin-17 (IL-17) genetic variants are associated with the severity of AB. A group...
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