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Article

Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.

The Pediatric infectious disease journal - 1 Apr 2009

Siezen Christine L E, Bont Louis, Hodemaekers Hennie M, Ermers Marieke J, Doornbos Gerda, Van't Slot Ruben, Wijmenga Ciska, Houwelingen Hans C van, Kimpen Jan L L, Kimman Tjeerd G, Hoebee Barbara, Janssen Riny

Abstract excerpt

Prematurity is a risk factor for severe respiratory syncytial virus bronchiolitis. We show that genetic factors in innate immune genes (IFNA13, IFNAR2, STAT2, IL27, NFKBIA, C3, IL1RN, TLR5), in innate and adaptive immunity (IFNG), and in airway remodeling genes (ADAM33 and TGFBR1), affect disease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19258923
DOI: 10.1097/INF.0b013e31818e2aa9

Genes

ADAM33
IFNA13
IFNAR2
IFNG
NFKBIA
STAT2
TGFBR1
TLR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19258923-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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