Article
Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.
The Journal of infectious diseases - 15 Sept 2007
Janssen Riny, Bont Louis, Siezen Christine L E, Hodemaekers Hennie M, Ermers Marieke J, Doornbos Gerda, van 't Slot Ruben, Wijmenga Ciska, Goeman Jelle J, Kimpen Jan L L, van Houwelingen Hans C, Kimman Tjeerd G, Hoebee Barbara
Abstract excerpt
BACKGROUND: Respiratory syncytial virus (RSV) is a common cause of severe lower respiratory tract infection in infants. Only a proportion of children infected with RSV require hospitalization. Because known risk factors for severe disease, such as premature birth, cannot fully explain differences in disease severity, genetic factors have been implicated. METHODS: To study the complexity of RSV susceptibility and...
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