Article
Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.
Pediatric pulmonology - 1 Jun 2010
Schuurhof Annemieke, Bont Louis, Siezen Christine L E, Hodemaekers Hennie, van Houwelingen Hans C, Kimman Tjeerd G, Hoebee Barbara, Kimpen Jan L L, Janssen Riny
Abstract excerpt
The predominance of severe respiratory syncytial virus (RSV) bronchiolitis in boys compared to girls is well known, but its mechanism is not yet understood. This is the first study focusing on gender-specific genetic factors affecting the risk of severe RSV infection using a previously described cohort. We determined 347 single-nucleotide polymorphisms (SNPs) in 470 children hospitalized for RSV infection, their...
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