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Tnni3k alleles influence ventricular mononuclear diploid cardiomyocyte frequency

7 Oct 2019

Abstract excerpt

Recent evidence implicates mononuclear diploid cardiomyocytes as a proliferative and regenerative subpopulation of the postnatal heart. The number of these cardiomyocytes is a complex trait showing substantial natural variation among inbred mouse strains based on the combined influences of multiple polymorphic genes. One gene confirmed to influence this parameter is the cardiomyocyte-specific kinase Tnni3k. Here,...

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PMID: 31589606
DOI: 10.1371/journal.pgen.1008354

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