Article
Cardiac interstitial tetraploid cells that escape replicative senescence are found in rodents but not large mammals
2019-01-16
Abstract excerpt
Ploidy for cardiomyocytes is well described but remains obscure in cardiac interstitial cells (CICs). Ploidy of c-kit+CICs (cCICs) were assessed using a combination of confocal, karyotypic, and flow cytometric assessments coupled with molecular and bioinformatic analyses. Fundamental differences were found between cultured rodent (rat, mouse) cCICs possessing mononuclear tetraploid (4n) content versus large mammal...
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Identifiers and source
- Literature Corpus work
- efa3ecee-d99e-5d49-99e6-285e262a1d74
- DOI
- 10.1101/521716