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Article

The whole-genome landscape of Burkitt lymphoma subtypes

26 Sept 2019

Abstract excerpt

Burkitt lymphoma (BL) is an aggressive, MYC-driven lymphoma comprising 3 distinct clinical subtypes: sporadic BLs that occur worldwide, endemic BLs that occur predominantly in sub-Saharan Africa, and immunodeficiency-associated BLs that occur primarily in the setting of HIV. In this study, we comprehensively delineated the genomic basis of BL through whole-genome sequencing (WGS) of 101 tumors representing all 3...

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Identifiers

PMID: 31558468
DOI: 10.1182/blood.2019001880

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