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Article

New clues to the molecular pathogenesis of Burkitt lymphoma revealed through next-generation sequencing.

Current opinion in hematology - 1 Jul 2014

Greenough Adrienne, Dave Sandeep S

Abstract excerpt

PURPOSE OF REVIEW: Burkitt lymphoma is an important clinical and model disease arising from B cells. Burkitt lymphoma is characterized by translocation of the c-MYC gene to an immunoglobulin enhancer region, resulting in enhanced cell proliferation and rapid tumor progression. The development of deep sequencing has widened the scope of genetic analysis to reveal the role of additional collaborating mutations in...

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Share to Burkitt Lymphoma
Share to DNA Copy Number Variations
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, myc

Share to High-Throughput Nucleotide Sequencing

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Share to Translocation, Genetic

Source

Identifiers

PMID: 24867287
DOI: 10.1097/MOH.0000000000000059

Genes

MYC
GNA13
SMARCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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