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Article

Comprehensive Transcriptome and Mutational Profiling of Endemic Burkitt Lymphoma Reveals EBV Type-Specific Differences.

Molecular cancer research : MCR - 1 May 2017

Kaymaz Yasin, Oduor Cliff I, Yu Hongbo, Otieno Juliana A, Ong'echa John Michael, Moormann Ann M, Bailey Jeffrey A

Abstract excerpt

Endemic Burkitt lymphoma (eBL) is the most common pediatric cancer in malaria-endemic equatorial Africa and nearly always contains Epstein-Barr virus (EBV), unlike sporadic Burkitt lymphoma (sBL) that occurs with a lower incidence in developed countries. Given these differences and the variable clinical presentation and outcomes, we sought to further understand pathogenesis by investigating transcriptomes using...

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Share to Burkitt Lymphoma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epstein-Barr Virus Infections

Share to Gene Regulatory Networks

Share to Herpesvirus 4, Human

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Share to Sequence Analysis, RNA

Source

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Identifiers

PMID: 28465297
DOI: 10.1158/1541-7786.MCR-16-0305
PMCID: PMC5471630

Genes

FOXO1
MSH6
PLCG2
PRKDC
PSMB10
PSMB8
PSMB9
PSME2
PTEN
RAD50
RPRD2
TFAP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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