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Targeted multiplex proteomics for molecular prescreening and biomarker discovery in metastatic colorectal cancer

19 Sept 2019

Abstract excerpt

Protein biomarkers are widely used in cancer diagnosis, prognosis, and prediction of treatment response. Here we introduce the use of targeted multiplex proteomics (TMP) as a tool to simultaneously measure a panel of 54 proteins involved in oncogenic, tumour suppression, drug metabolism and resistance, in patients with metastatic colorectal cancer (mCRC). TMP provided valuable diagnostic information by unmasking...

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PMID: 31537838
DOI: 10.1038/s41598-019-49867-7

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