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Article

Developing proteomics‐based biomarkers for colorectal neoplasms for clinical practice: Opportunities and challenges

19 Dec 2012

Abstract excerpt

Colorectal cancer (CRC) arises from the normal colon epithelium through the accumulation of genetic mutations and epigenetic alterations that are associated with progression along the histological adenoma-adenocarcinoma sequence. Elucidating the molecular alterations underlying disease progression will not only provide insight into the behavior of the tumors, but also could lead to the discovery of useful...

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PMID: 23255431
DOI: 10.1002/prca.201200071

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