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Article

ΔNp63α suppresses cells invasion by downregulating PKCγ/Rac1 signaling through miR-320a

12 Sept 2019

Abstract excerpt

ΔNp63α, a member of the p53 family of transcription factors, is overexpressed in a number of cancers and plays a role in proliferation, differentiation, migration, and invasion. ΔNp63α has been shown to regulate several microRNAs that are involved in development and cancer. We identified miRNA miR-320a as a positively regulated target of ΔNp63α. Previous studies have shown that miR-320a is downregulated in...

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PMID: 31515469
DOI: 10.1038/s41419-019-1921-6

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