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ERK3 is transcriptionally upregulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in Non-Melanoma Skin Cancers

2020-07-02

Abstract excerpt

<h4>Background: </h4> p63, a member of the p53 gene family, is an important regulator for epithelial tissue growth and development. ∆Np63α is the main isoform of p63 and highly expressed in Non-melanoma skin cancer (NMSC). Extracellular signal-regulated kinase 3 (ERK3) is an atypical mitogen-activated protein kinase (MAPK) whose biochemical features and cellular regulation are distinct from those of conventional M...

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Literature Corpus work
ed499d29-90de-5b00-ba04-ef9fd73c4f2a
DOI
10.21203/rs.2.23512/v2
Open publication

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