Article
ΔNp63 promotes UM‑UC‑3 cell invasiveness and migration through claudin‑1 in vitro.
Molecular medicine reports - 1 Mar 2013
Jing Peng, Zou Jiaqiong, Zhang Jun, Jiang Xingliang
Abstract excerpt
The p63 gene, a member of the p53 gene family, has two different promoter usage‑generating proteins that contain or lack (ΔN) an NH2‑terminus. Although p53 and p63 have high sequence and structural similarities, the molecules differ in function and expression profiles. p63 is critical for the development of epithelial organs or tissues, including the epidermis and...
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