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Article

ΔNp63 regulates cell proliferation, differentiation, adhesion, and migration in the BL2 subtype of basal-like breast cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2016

Orzol Paulina, Nekulova Marta, Holcakova Jitka, Muller Petr, Votesek Borivoj, Coates Philip J

Abstract excerpt

Triple-negative breast cancers (TNBC) comprise a heterogeneous subgroup of tumors with a generally poor prognosis. Subclassification of TNBC based on genomic analyses shows that basal-like TNBCs, specifically the basal A or BL2 subtype, are characterized by the expression of ΔNp63, a transcription factor that has been attributed a variety of roles in the regulation of proliferation, differentiation, and cell...

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PMID: 26825981
DOI: 10.1007/s13277-016-4880-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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