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Article

Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis

22 Aug 2019

Abstract excerpt

IMPORTANCE: Genetic variants associated with primary open-angle glaucoma (POAG) are known to influence disease risk. However, the clinical effect of associated variants individually or in aggregate is not known. Genetic risk scores (GRS) examine the cumulative genetic load by combining individual genetic variants into a single measure, which is assumed to have a larger effect and increased power to detect...

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Identifiers

PMID: 31436842
DOI: 10.1001/jamaophthalmol.2019.3109

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