Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human colorectal cancer-derived carcinoma associated fibroblasts promote CD44-mediated adhesion of colorectal cancer cells to endothelial cells by secretion of HGF

24 Jul 2019

Abstract excerpt

BACKGROUND: Carcinoma-associated fibroblasts (CAFs) are dominant components of tumor microenvironment, which has been reported to promote development, progression, and metastasis of cancer. However, the role of CAFs during adhesion process remains unknown. It has been hypothesized that CAFs contribute to adhesion to endothelial cells of colorectal cancer (CRC) via HGF/c-Met pathway. METHODS: Clinical specimen and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cell Adhesion Molecules Research
Share to Proteoglycans and glycosaminoglycans research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31367190
DOI: 10.1186/s12935-019-0914-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human colorectal cancer-derived carcinoma associated fibroblasts promote CD44-mediated adhesion of colorectal cancer cells to endothelial cells by secretion of HGFPMID 31367190Read ↗

Cancer associated fibroblasts (CAFs) in tumor microenvironmentSemantic proximity Read ↗

Organ Specificity and Heterogeneity of Cancer-Associated Fibroblasts in Colorectal CancerSemantic proximity Read ↗

Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progressionSemantic proximity Read ↗

[Colorectal fibroblasts promote malignant phenotype of colorectal cancer cells by activating the ERK signaling pathway].Semantic proximity Read ↗

Functional heterogeneity of cancer-associated fibroblasts from human colon tumors shows specific prognostic gene expression signature.Semantic proximity Read ↗

Regulation of intestinal myofibroblasts by KRas-mutated colorectal cancer cells through heparin-binding epidermal growth factor-like growth factor.Semantic proximity Read ↗

Fibroblast surface-associated FGF-2 promotes contact-dependent colorectal cancer cell migration and invasion through FGFR-SRC signaling and integrin αvβ5-mediated adhesionSemantic proximity Read ↗

Cancer-associated fibroblasts are positively correlated with metastatic potential of human gastric cancersSemantic proximity Read ↗

HIF-1α promotes the migration and invasion of cancer-associated fibroblasts by miR-210Semantic proximity Read ↗

Hepatocellular carcinoma cells cause different responses in expressions of cancer‐promoting genes in different cancer‐associated fibroblastsSemantic proximity Read ↗

HGF/c-MET Axis in Tumor Microenvironment and Metastasis FormationSemantic proximity Read ↗

The role of multipotent cancer associated fibroblasts in hepatocarcinogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.