Article
The role of multipotent cancer associated fibroblasts in hepatocarcinogenesis.
BMC cancer - 27 Mar 2015
Sukowati Caecilia Hapsari Ceriapuri, Anfuso Beatrice, Crocé Lory Saveria, Tiribelli Claudio
Abstract excerpt
BACKGROUND: The presence of tumor supporting cells in various cancer, including in hepatocellular carcinoma (HCC), has become an important target in the study of carcinogenesis. The cancer-associated fibroblast (CAF), one of the most important cellular components in the cancer stroma, might contribute to the progression of the disease due to its plasticity, a behavior of the stem cells. In this study, we...
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