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Article

HGF/c-MET Axis in Tumor Microenvironment and Metastasis Formation

22 Jan 2015

Abstract excerpt

Tumor metastases are responsible for approximately 90% of all cancer-related deaths. Metastasis formation is a multistep process that requires acquisition by tumor cells of a malignant phenotype that allows them to escape from the primary tumor site and invade other organs. Each step of this mechanism involves a deep crosstalk between tumor cells and their microenvironment where the host cells play a key role in...

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PMID: 28536400
DOI: 10.3390/biomedicines3010071

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