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Hepatocellular carcinoma cells cause different responses in expressions of cancer‐promoting genes in different cancer‐associated fibroblasts

13 Oct 2012

Abstract excerpt

Cancer-associated fibroblast (CAF) is one of the most crucial components of the tumor microenvironment to promote the invasiveness of cancer cells. The interactions between cancer cells and CAFs are bidirectional. Our recent study showed that up-regulations of chemokine (C-C motif) ligand 2 (CCL2), chemokine (C-C motif) ligand 26 (CCL26), interleukin 6 (IL6), and lysyl oxidase-like 2 (LOXL2) genes in cancer cells...

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PMID: 23684136
DOI: 10.1016/j.kjms.2012.08.012

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