Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Colorectal fibroblasts promote malignant phenotype of colorectal cancer cells by activating the ERK signaling pathway].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 20 Oct 2024

Xi X, Deng T, DU B

Abstract excerpt

OBJECTIVE: To investigate the effect of human colorectal fibroblast (CCD-18Co)-conditioned medium (CCD18-Co-CM) on biological behaviors of colorectal cancer (CRC) cells and explore the possible molecular mechanisms. METHODS: Real-time cellular analysis (RTCA), clone formation assay and wound healing assay were used to analyze the changes in proliferation, clone formation, and migration abilities of CRC cell lines...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caco-2 Cells
Share to Cell Movement
Share to Culture Media, Conditioned

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HCT116 Cells

Share to Indazoles

Share to MAP Kinase Signaling System

Share to Piperazines

Share to STAT3 Transcription Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 39523086
DOI: 10.12122/j.issn.1673-4254.2024.10.04
PMCID: PMC11526459

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Colorectal fibroblasts promote malignant phenotype of colorectal cancer cells by activating the ERK signaling pathway].PMID 39523086Read ↗

Drug-Resistance Biomarkers in Patient-Derived Colorectal Cancer Organoid and Fibroblast Co-Culture SystemSemantic proximity Read ↗

2D- and 3D-Based Intestinal Stem Cell Cultures for Personalized MedicineSemantic proximity Read ↗

Cancer-associated fibroblasts induced by colorectal cancer cells inhibit γδT cells killing function through the ERK/COX-2/PGE2 pathwaysSemantic proximity Read ↗

Oxidative stress induced autophagy in cancer associated fibroblast enhances proliferation and metabolism of colorectal cancer cellsSemantic proximity Read ↗

The effects of mesenchymal stem cells on the chemotherapy of colorectal cancerSemantic proximity Read ↗

Dedifferentiation process driven by TGF-beta signaling enhances stem cell properties in human colorectal cancerSemantic proximity Read ↗

Unveiling the Mechanisms to Bypass KRAS Inhibition: <i>In Vitro</i> Insights into the Influence of Fibroblast-SecretomeSemantic proximity Read ↗

Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis.Semantic proximity Read ↗

Differences and Similarities between Colorectal Cancer Cells and Colorectal Cancer Stem Cells: Molecular Insights and ImplicationsSemantic proximity Read ↗

Establishment of a human colorectal cancer cell line P6C with stem cell properties and resistance to chemotherapeutic drugsSemantic proximity Read ↗

Regulation of intestinal myofibroblasts by KRas-mutated colorectal cancer cells through heparin-binding epidermal growth factor-like growth factor.Semantic proximity Read ↗

Targeting Colorectal Cancer Stem Cells as an Effective Treatment for Colorectal Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.