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Article

HIF-1α promotes the migration and invasion of cancer-associated fibroblasts by miR-210

1 Jan 2021

Abstract excerpt

Metastasis is the major cause of death in colorectal cancer (CRC) patients. Inhibition of metastasis will prolong the survival of patients with CRC. Cancer cells bring their own soil, cancer-associated fibroblasts (CAFs), to metastasize together, promoting the survival and colonization of circulating cancer cells. However, the mechanism by which CAFs metastasize remains unclear. In this study, CAFs were derived...

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Identifiers

PMID: 34631221
DOI: 10.14336/ad.2021.0315

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