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Article

Genomic modeling of hepatitis B virus integration frequency in the human genome

29 Jul 2019

Abstract excerpt

Hepatitis B infection is a world-wide public health burden causing serious liver complications. Previous studies suggest that hepatitis B integration into the human genome plays a crucial role in triggering oncogenic process and may also constitutively produce viral antigens. Despite the progress in HBV biology and sequencing technology, our fundamental understanding of how many hepatocytes in the liver actually...

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PMID: 31356634
DOI: 10.1371/journal.pone.0220376

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