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Article

Genetics and epigenetics of osteoarthritis.

Maturitas - 1 Mar 2012

Reynard Louise N, Loughlin John

Abstract excerpt

Osteoarthritis (OA) is a common age-related disease that affects the tissues of the synovial joint, leading to loss of function and pain. It impacts on both patient morbidity and mortality. It is a complex, polygenic disease that lacks any large-effect susceptibility loci. Instead, OA susceptibility alleles individually contribute only modestly to the overall disease risk, making their identification challenging....

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PMID: 22209350
DOI: 10.1016/j.maturitas.2011.12.001

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GDF5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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