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Article

A novel variant in GLIS3 is associated with osteoarthritis.

Annals of the rheumatic diseases - 1 Apr 2018

Casalone Elisabetta, Tachmazidou Ioanna, Zengini Eleni, Hatzikotoulas Konstantinos, Hackinger Sophie, Suveges Daniel, Steinberg Julia, Rayner Nigel William, Wilkinson Jeremy Mark, Panoutsopoulou Kalliope, Zeggini Eleftheria

Abstract excerpt

OBJECTIVES: Osteoarthritis (OA) is a complex disease, but its genetic aetiology remains poorly characterised. To identify novel susceptibility loci for OA, we carried out a genome-wide association study (GWAS) in individuals from the largest UK-based OA collections to date. METHODS: We carried out a discovery GWAS in 5414 OA individuals with knee and/or hip total joint replacement (TJR) and 9939 population-based...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29436472
DOI: 10.1136/annrheumdis-2017-211848
PMCID: PMC5890630

Genes

GLIS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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