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Article

Knockdown of spliceosome U2AF1 significantly inhibits the development of human erythroid cells

29 May 2019

Abstract excerpt

U2AF1 (U2AF35) is the small subunit of the U2 auxiliary factor (U2AF) that constitutes the U2 snRNP (small nuclear ribonucleoproteins) of the spliceosome. Here, we examined the function of U2AF1 in human erythropoiesis. First, we examined the expression of U2AF1 during in vitro human erythropoiesis and showed that U2AF1 was highly expressed in the erythroid progenitor burst-forming-unit erythroid (BFU-E) cell...

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PMID: 31144421
DOI: 10.1111/jcmm.14370

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