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Erythropoiesis: Model systems, molecular regulators, and developmental programs

20 Jul 2009

Abstract excerpt

Human erythropoiesis is a complex multistep developmental process that begins at the level of pluripotent hematopoietic stem cells (HSCs) at bone marrow microenvironment (HSCs niche) and terminates with the production of erythrocytes (RBCs). This review covers the basic and contemporary aspects of erythropoiesis. These include the: (a) cell-lineage restricted pathways of differentiation originated from HSCs and...

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PMID: 19621348
DOI: 10.1002/iub.226

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