Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Immune Contexture Associates with the Genomic Landscape in Lung Adenomatous Premalignancy

30 May 2019

Abstract excerpt

Abstract Epithelial cells in the field of lung injury can give rise to distinct premalignant lesions that may bear unique genetic aberrations. A subset of these lesions may escape immune surveillance and progress to invasive cancer; however, the mutational landscape that may predict progression has not been determined. Knowledge of premalignant lesion composition and the associated microenvironment is critical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Cancer Immunotherapy and Biomarkers
Share to Lung Cancer Treatments and Mutations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31142513
DOI: 10.1158/0008-5472.can-19-0153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Immune Contexture Associates with the Genomic Landscape in Lung Adenomatous PremalignancyPMID 31142513Read ↗

Genomic Landscape of Atypical Adenomatous Hyperplasia Reveals Divergent Modes to Lung Adenocarcinoma.Semantic proximity Read ↗

Archetype analysis of lung adenocarcinoma premalignancy links heterogeneity in premalignant lesions to diverging features of invasive diseaseSemantic proximity Read ↗

Multiomics Analysis Reveals Molecular Changes during Early Progression of Precancerous Lesions to Lung Adenocarcinoma in Never-Smokers.Semantic proximity Read ↗

Mechanisms of Progression and Heterogeneity in Multiple Nodules of Lung AdenocarcinomaSemantic proximity Read ↗

Up-regulated tumor intrinsic growth potential and decreased immune function orchestrate the evolution of lung adenocarcinomaSemantic proximity Read ↗

Genetic Alterations in Preinvasive Lung Synchronous Lesions.Semantic proximity Read ↗

An Investigation of the Immune Microenvironment and Genome during Lung Adenocarcinoma DevelopmentSemantic proximity Read ↗

Genomic and immune heterogeneity of multiple synchronous lung adenocarcinoma at different developmental stagesSemantic proximity Read ↗

Genomic and immune heterogeneity of multiple synchronous lung adenocarcinoma at different developmental stages.Semantic proximity Read ↗

Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinomaSemantic proximity Read ↗

Insights Into Lung Cancer Immune-Based Biology, Prevention, and Treatment.Semantic proximity Read ↗

Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.