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Article

INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4

15 Apr 2019

Abstract excerpt

The p53 protein is a tumour suppressor and transcription factor that regulates the expression of target genes involved in numerous stress responses systems. In this study, we designed a screening strategy using DNA damage‑induced mouse and human transcriptome data to identify novel downstream targets of p53. Our method selected genes with an induced expression in multiple organs of X‑ray‑irradiated p53 wild‑type...

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Identifiers

PMID: 31081062
DOI: 10.3892/ijo.2019.4786

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