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Article

Role of p53 in Regulating Radiation Responses

21 Jul 2022

Abstract excerpt

gene was found to express multiple p53 splice variants (isoforms) in a physiological, tissue-dependent manner. The various genes that up- and down-regulated p53 are involved in cell viability, senescence, inflammation, and carcinogenesis. Moreover, p53 affects the radioadaptive response. Given that several studies have already been published on p53, this review presents its role in the response to gamma...

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PMID: 35888186
DOI: 10.3390/life12071099

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