Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pharmacogenetics of Sertraline Tolerability and Response in Pediatric Anxiety and Depressive Disorders

8 May 2019

Abstract excerpt

Objective: To determine whether genetic variants in a pharmacokinetic gene (the number of CYP2C19 reduced function alleles [RFAs]), and in pharmacodynamic genes (HTR2A, SLC6A4, and GRIK4) influence sertraline tolerability and response in a cohort of pediatric patients with anxiety and depressive disorders. Methods: A retrospective analysis was performed using the electronic medical record data of 352 patients <19...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Attention Deficit Hyperactivity Disorder
Share to Bipolar Disorder and Treatment
Share to Child and Adolescent Psychosocial and Emotional Development

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31066578
DOI: 10.1089/cap.2019.0017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pharmacogenetics of Sertraline Tolerability and Response in Pediatric Anxiety and Depressive DisordersPMID 31066578Read ↗

Sertraline dosing trends in children and adolescents stratified by CYP2C19 genotype.Semantic proximity Read ↗

Effect of Individual and Combined Cytochrome P450 Activity Scores on Symptom Improvement and Side Effects in Youth Treated With Sertraline.Semantic proximity Read ↗

Escitalopram and Sertraline Population Pharmacokinetic Analysis in Pediatric Patients.Semantic proximity Read ↗

Pharmacogenetics to Predict Adverse Events Associated With Antidepressants.Semantic proximity Read ↗

Impact of CYP2C19 genotype on sertraline exposure in 1200 Scandinavian patients.Semantic proximity Read ↗

Impact of the novel CYP2C:TG haplotype and CYP2B6 variants on sertraline exposure in a large patient population.Semantic proximity Read ↗

Impact of Cytochrome P450 Genetic Variation on Patient-Reported Symptom Improvement and Side Effects Among Children and Adolescents Treated with Fluoxetine.Semantic proximity Read ↗

Pharmacogenetics of selective serotonin reuptake inhibitors (SSRI): A serotonin reuptake transporter (SERT)-based approach.Semantic proximity Read ↗

Effect of Polymorphisms on the Pharmacokinetics, Pharmacodynamics and Safety of Sertraline in Healthy Volunteers.Semantic proximity Read ↗

Pharmacogenetics of the serotonin transporter.Semantic proximity Read ↗

Associations of CYP2B6, CYP2C19, and CYP2D6 isoforms and phenoconversion with sertraline pharmacokinetics.Semantic proximity Read ↗

Serum concentrations of sertraline and N-desmethyl sertraline in relation to CYP2C19 genotype in psychiatric patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.