Article
Escitalopram and Sertraline Population Pharmacokinetic Analysis in Pediatric Patients.
Clinical pharmacokinetics - 1 Nov 2023
Poweleit Ethan A, Taylor Zachary L, Mizuno Tomoyuki, Vaughn Samuel E, Desta Zeruesenay, Strawn Jeffrey R, Ramsey Laura B
Abstract excerpt
BACKGROUND AND OBJECTIVE: Escitalopram and sertraline are commonly prescribed for anxiety and depressive disorders in children and adolescents. The pharmacokinetics (PK) of these medications have been evaluated in adults and demonstrate extensive variability, but studies in pediatric patients are limited. Therefore, we performed a population PK analysis for escitalopram and sertraline in children and adolescents...
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