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Article

Mild cognitive impairment in de novo Parkinson's disease: A neuromelanin MRI study in locus coeruleus

2 Apr 2019

Abstract excerpt

BACKGROUND: We aimed to investigate neuromelanin-sensitive magnetic resonance imaging (NM-MRI) features in the locus coeruleus of de novo Parkinson's disease patients with different cognitive states and to determine whether these features are associated with cognitive impairment. METHODS: Three groups of subjects were recruited in this study, including patients with de novo PD with mild cognitive impairment (n =...

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PMID: 30938892
DOI: 10.1002/mds.27682

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