Article

A Longitudinal Neuromelanin MRI Processing Framework Reduces Measurement Variability and Improves Precision in Parkinson’s Disease

2026-07-27

Abstract excerpt

<h4>Background</h4> Neuromelanin-MRI enables in vivo assessment of the substantia nigra (SN) and locus coeruleus (LC) in individuals with Parkinson’s disease (PD), yet longitudinal studies rely on cross-sectional processing that may introduce measurement variability and confound estimates of change over time. <h4>Objectives</h4> In this paper, a longitudinal neuromelanin-MRI processing framework is presented t...

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Literature Corpus work: 225afb0c-36b2-5939-97c5-ebbfe124354e
DOI: 10.64898/2026.07.24.26358895

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