Article

Fully automated segmentation of the locus coeruleus: application to assess the effects of age, sex and education

2025-01-09

Abstract excerpt

<h4>Background</h4> Locus coeruleus (LC) imaging using neuromelanin-sensitive (NM) MRI sequences is a promising biomarker for detecting early Alzheimer’s Disease (AD) and Parkinson’s Disease (PD). Although semi or fully automatic approaches have been developed to estimate LC integrity by measuring its intensity, these techniques most often rely on a single template built in a standardized space and/or depend on a...

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Literature Corpus work: 24f81004-41bc-53ce-a208-1ca328d69220
DOI: 10.1101/2025.01.08.25320149

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